Thank you, Minister, and that assurance is good to hear, because we have, of course, heard separate stories over the last few days of some supply chain and production challenges, and we should anticipate that there will be glitches as we go along; it's not going to be perfect. Firstly, we heard of the Oxford-AstraZeneca vaccine challenges, because one of the four batches of the vaccine over the weekend produced for Wales was delayed. And then we heard, of course, of six EU health Ministers putting in writing to the European Commission their severe concerns about delivery delays on the Pfizer-BioNTech vaccine. So, can you tell the Senedd whether these sorts of challenges that will happen from time to time with the supply chain and manufacture will impact on the safe and rapid deployment of the vaccines in Wales and across the UK, or whether the planning that you've got in place can mitigate these problems in the vaccine supply and manufacture?